SHMT1 antibody (AA 1-470)

Catalog No. ABIN7869391

The Mouse Monoclonal anti-SHMT1 antibody (Clone 9C7) (ABIN7869391) specifically detects SHMT1 in WB, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for SHMT1 antibody (AA 1-470) (ABIN7869391)

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This SHMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 9C7

Product Details anti-SHMT1 Antibody

Binding Specificity: AA 1-470

Purpose: SHMT Antibody / SHMT1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-S470) was used as the immunogen for the SHMT antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the SHMT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SHMT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SHMT1

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Alternative Name: SHMT

Background: This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.

UniProt: P34896