TRIM25 antibody (AA 1-590)
Quick Overview for TRIM25 antibody (AA 1-590) (ABIN7869487)
Target
See all TRIM25 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 1-590
-
Purpose
- Trim25 Antibody / Efp
-
Purification
- Antigen affinity purified
-
Immunogen
- Recombinant mouse protein (amino acids M1-H590) was used as the immunogen for the Trim25 antibody.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal dilution of the Trim25 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- After reconstitution, the Trim25 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
-
Alternative Name
- Trim25
-
Background
- Tripartite motif-containing protein 25 is a protein that in humans is encoded by the TRIM25 gene. It is mapped to 17q22. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
-
UniProt
- Q61510
Target
-