TRIM25 antibody (AA 1-610)

Catalog No. ABIN7869495

The Rabbit Polyclonal anti-TRIM25 antibody is suitable to detect TRIM25 in samples from Human. It has been validated for WB, ELISA, IF, FACS and IHC (p).

Quick Overview for TRIM25 antibody (AA 1-610) (ABIN7869495)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM25 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRIM25 Antibody

Binding Specificity: AA 1-610

Purpose: TRIM25 Antibody / EFP

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-A610) was used as the immunogen for the TRIM25 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TRIM25 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TRIM25 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Alternative Name: TRIM25

Background: Tripartite motif-containing protein 25, also called 'Estrogen-responsive finger protein' or 'EFP,' is a protein that in humans is encoded by the TRIM25 gene. It is mapped to 17q22. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

UniProt: Q14258