slc25a13 antibody (AA 1-643)
Quick Overview for slc25a13 antibody (AA 1-643) (ABIN7869514)
Target
See all slc25a13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-643
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Purpose
- Citrin Antibody / ARALAR2 / SLC25A13
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Purification
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids M1-A643) was used as the immunogen for the Citrin antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the Citrin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the Citrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- slc25a13 (Solute Carrier Family 25, Member 13 (Citrin) (slc25a13))
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Alternative Name
- Citrin
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Background
- Citrin also known as solute carrier family 25, member 13 (also called Citrin and ARALAR-related gene 2) is a protein which in humans is encoded by the SLC25A13 gene. This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9UJS0
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Pathways
- Ribonucleoside Biosynthetic Process, Dicarboxylic Acid Transport
Target
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