The Mouse Monoclonal anti-CCL18 antibody (Clone CCL18-3744) (ABIN7869604) specifically detects CCL18 in IHC (p).
The antibody is reactive with Human samples.
Optimal dilution of the CCL18 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the CCL18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
CCL18
(Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
Alternative Name
CCL18
Background
Chemokines are members of a superfamily of small inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20 to 50 % homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1a, MIP-1b, MIP-2, MIP-3a, MIP-3b, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. MIP-4 is constituitively expressed in several normal tissues and is highly expressed in plasma.