Phospholipase D2 antibody (AA 10-39)
Quick Overview for Phospholipase D2 antibody (AA 10-39) (ABIN7869702)
Target
See all Phospholipase D2 (PLD2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 10-39
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Purpose
- Phospholipase D2 Antibody / PLD2
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 10-39 from the human protein was used as the immunogen for the Phospholipase D2 antibody.
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Isotype
- IgG
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the Phospholipase D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Phospholipase D2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Phospholipase D2 (PLD2)
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Alternative Name
- Phospholipase D2
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Background
- Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[OMIM]
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UniProt
- O14939
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Pathways
- RTK Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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