CHD8 antibody (AA 10-428)

Catalog No. ABIN7869704

This Rabbit Polyclonal antibody specifically detects CHD8 in WB, IHC (p), ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for CHD8 antibody (AA 10-428) (ABIN7869704)

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Flow Cytometry (FACS)

Product Details anti-CHD8 Antibody

Binding Specificity: AA 10-428

Purpose: CHD8 Antibody / Chromodomain-helicase-DNA-binding protein 8

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (D10-A428) was used as the immunogen for the CHD8 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CHD8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CHD8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CHD8

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Alternative Name: CHD8

Background: Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene. This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants.

UniProt: Q9HCK8

Pathways: Chromatin Binding