SYK antibody (AA 10-635)

Catalog No. ABIN7869715

The Rabbit Polyclonal anti-SYK antibody (ABIN7869715) specifically detects SYK in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SYK antibody (AA 10-635) (ABIN7869715)

Target: SYK (Spleen tyrosine Kinase (SYK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-SYK Antibody

Binding Specificity: AA 10-635

Purpose: SYK Antibody / Spleen tyrosine kinase

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids A10-N635) was used as the immunogen for the SYK antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SYK antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SYK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SYK

Target: SYK (Spleen tyrosine Kinase (SYK))

Alternative Name: SYK

Background: Spleen tyrosine kinase, also known as Syk, is an enzyme which in humans is encoded by the SYK gene. It is mapped to 9q22.2. This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P43405

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling