DOCK1 antibody (AA 100-1732)

Catalog No. ABIN7869725

This Rabbit Polyclonal antibody specifically detects DOCK1 in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for DOCK1 antibody (AA 100-1732) (ABIN7869725)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-DOCK1 Antibody

Binding Specificity: AA 100-1732

Purpose: DOCK1 Antibody

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids S100-T1732) was used as the immunogen for the DOCK1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DOCK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DOCK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Alternative Name: DOCK1

Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor