SULT1E1 antibody (AA 100-294)

Catalog No. ABIN7869811

The Mouse Monoclonal anti-SULT1E1 antibody (Clone SULT1E1-7124) (ABIN7869811) specifically detects SULT1E1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SULT1E1 antibody (AA 100-294) (ABIN7869811)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SULT1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SULT1E1-7124

Product Details anti-SULT1E1 Antibody

Binding Specificity: AA 100-294

Purpose: Estrogen Sulfotransferase Antibody / SULT1E1

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 100-294) from the human protein was used as the immunogen for the Estrogen Sulfotransferase antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the Estrogen Sulfotransferase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Estrogen Sulfotransferase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Alternative Name: Estrogen Sulfotransferase

Background: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis