Amphiregulin antibody (AA 101-180)

Catalog No. ABIN7869891

The Rabbit Polyclonal anti-Amphiregulin antibody is suitable to detect Amphiregulin in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for Amphiregulin antibody (AA 101-180) (ABIN7869891)

Target: Amphiregulin (AREG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Amphiregulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-Amphiregulin Antibody

Binding Specificity: AA 101-180

Purpose: AREG Antibody / Amphiregulin

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S101-R180) was used as the immunogen for the AREG antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the AREG antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the AREG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Amphiregulin

Target: Amphiregulin (AREG)

Alternative Name: AREG

Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

UniProt: P15514

Pathways: RTK Signaling, EGFR Signaling Pathway