CHI3L1 antibody (AA 103-383)

Catalog No. ABIN7869930

The Rabbit Polyclonal anti-CHI3L1 antibody is suitable to detect CHI3L1 in samples from Human, Mouse and Rat. It has been validated for WB, IF and ELISA.

Quick Overview for CHI3L1 antibody (AA 103-383) (ABIN7869930)

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHI3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-CHI3L1 Antibody

Binding Specificity: AA 103-383

Purpose: YKL-40 Antibody / CHI3L1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids S103-T383) was used as the immunogen for the YKL-40 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the YKL-40 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the YKL-40 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CHI3L1

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Alternative Name: YKL-40

Background: Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40 kDa in size that in humans is encoded by the CHI3L1 gene. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

UniProt: P36222