Ephrin A1 antibody (AA 1062-1090)

Catalog No. ABIN7869996

The Rabbit Polyclonal anti-Ephrin A1 antibody is suitable to detect Ephrin A1 in samples from Human and Mouse. It has been validated for WB, IHC (p) and FACS.

Quick Overview for Ephrin A1 antibody (AA 1062-1090) (ABIN7869996)

Target: Ephrin A1 (EFNA1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Ephrin A1 Antibody

Binding Specificity: AA 1062-1090

Purpose: EFL1 Antibody / EFTUD1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1062-1090 from the human protein was used as the immunogen for the EFL1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the EFL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EFL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Ephrin A1

Target: Ephrin A1 (EFNA1)

Alternative Name: EFL1

Background: Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. [UniProt]

UniProt: Q7Z2Z2

Pathways: RTK Signaling