VEGFC antibody (AA 108-223)

Catalog No. ABIN7870024

The Rabbit Polyclonal anti-VEGFC antibody (ABIN7870024) specifically detects VEGFC in WB and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for VEGFC antibody (AA 108-223) (ABIN7870024)

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VEGFC Antibody

Binding Specificity: AA 108-223

Purpose: Vegfc Antibody / Vascular endothelial growth factor C

Purification: Antigen affinity purified

Immunogen: An E.coli-derived mouse recombinant protein (A108-R223) was used as the immunogen for the Vegfc antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Vegfc antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Vegfc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for VEGFC

Target: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Alternative Name: Vegfc

Background: Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation, positive regulation of angiogenesis, and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, positive regulation of lymphangiogenesis, and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery, brain, cardiovascular system, embryo mesenchyme, and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C).

UniProt: P97953

Pathways: RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2