TJP1 antibody (AA 1178-1527)

Catalog No. ABIN7870254

The Mouse Monoclonal anti-TJP1 antibody is suitable to detect TJP1 in samples from Human. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for TJP1 antibody (AA 1178-1527) (ABIN7870254)

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TJP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3E12-

Product Details anti-TJP1 Antibody

Binding Specificity: AA 1178-1527

Purpose: TJP1 Antibody / ZO-1

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids H1178-F1527) was used as the immunogen for the TJP1 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the TJP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TJP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TJP1

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Alternative Name: TJP1

Background: Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. It is mapped to 15q13.1. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. It has been found that injected CagA associates with the epithelial tight-junction scaffolding protein TJP1 and the transmembrane protein junctional adhesion molecule, causing an ectopic assembly of tight junction components at sites of bacterial attachment, and altering the composition and function of the apical-junctional complex.

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization