CENPI antibody (AA 120-604)

Catalog No. ABIN7870314

The Rabbit Polyclonal anti-CENPI antibody is suitable to detect CENPI in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for CENPI antibody (AA 120-604) (ABIN7870314)

Target: CENPI (Centromere Protein I (CENPI))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-CENPI Antibody

Binding Specificity: AA 120-604

Purpose: CENPI Antibody / Centromere protein I

Purification: Antigen affinity purified

Immunogen: Recombinant human CENPI protein (amino acids K120-C604) was used as the immunogen for the CENPI antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CENPI antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CENPI antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CENPI

Target: CENPI (Centromere Protein I (CENPI))

Alternative Name: CENPI

Background: Centromere protein I is a protein that in humans is encoded by the CENPI gene. This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13.

UniProt: Q92674