BCL10 antibody (AA 122-168)

Catalog No. ABIN7870335

The Mouse Monoclonal anti-BCL10 antibody is suitable to detect BCL10 in samples from Human. It has been validated for IHC (p).

Quick Overview for BCL10 antibody (AA 122-168) (ABIN7870335)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL10 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 151

Product Details anti-BCL10 Antibody

Binding Specificity: AA 122-168

Purpose: Bcl10 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 122-168) was used as the immunogen for this Bcl10 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Bcl10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Bcl10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Alternative Name: Bcl10

Background: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55 % of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins