P-Cadherin antibody (AA 126-336)

Catalog No. ABIN7870395

The Mouse Monoclonal anti-P-Cadherin antibody is suitable to detect P-Cadherin in samples from Human. It has been validated for WB and IF.

Quick Overview for P-Cadherin antibody (AA 126-336) (ABIN7870395)

Target: P-Cadherin (CDH3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 3C9

Product Details anti-P-Cadherin Antibody

Binding Specificity: AA 126-336

Purpose: CDH3 Antibody / P-Cadherin

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids Q126-H336) was used as the immunogen for the CDH3 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the CDH3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CDH3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: CDH3

Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

UniProt: P22223