RAPGEF2 antibody (AA 1266-1499)

Catalog No. ABIN7870398

The Rabbit Polyclonal anti-RAPGEF2 antibody is suitable to detect RAPGEF2 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for RAPGEF2 antibody (AA 1266-1499) (ABIN7870398)

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RAPGEF2 Antibody

Binding Specificity: AA 1266-1499

Purpose: RAPGEF2 Antibody

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids S1266-V1499) was used as the immunogen for the RAPGEF2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RAPGEF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RAPGEF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RAPGEF2

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Alternative Name: RAPGEF2

Background: Rap guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the RAPGEF2 gene. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.

UniProt: Q9Y4G8

Pathways: Neurotrophin Signaling Pathway