ICMT antibody (AA 13-284)

Catalog No. ABIN7870466

This Rabbit Polyclonal antibody specifically detects ICMT in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for ICMT antibody (AA 13-284) (ABIN7870466)

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ICMT Antibody

Binding Specificity: AA 13-284

Purpose: ICMT Antibody / Protein-S-isoprenylcysteine O-methyltransferase

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids E13-L284) was used as the immunogen for the ICMT antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ICMT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ICMT Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ICMT

Target: ICMT (Isoprenylcysteine Carboxyl Methyltransferase (ICMT))

Alternative Name: ICMT

Background: Protein-S-isoprenylcysteine O-methyltransferase is an enzyme that in humans is encoded by the ICMT gene. This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

UniProt: O60725