MARCO antibody (AA 13-40)

Catalog No. ABIN7870474

The Rabbit Polyclonal anti-MARCO antibody (ABIN7870474) specifically detects MARCO in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MARCO antibody (AA 13-40) (ABIN7870474)

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCO antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MARCO Antibody

Binding Specificity: AA 13-40

Purpose: MARCO Antibody / SCARA2

Purification: Antigen affinity

Immunogen: A portion of amino acids 13-40 from the human protein was used as the immunogen for this MARCO antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MARCO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MARCO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Alternative Name: MARCO

Background: MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response