The Rabbit Polyclonal anti-HJURP antibody (ABIN7870480) specifically detects HJURP in WB, ELISA and FACS.
The antibody is reactive with Mouse and Rat samples.
HJURP
Reactivity: Human
WB, ELISA, IHC, FACS
Host: Rabbit
Polyclonal
PE
Application Notes
Optimal dilution of the Hjurp antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Hjurp antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
HJURP
(Holliday Junction Recognition Protein (HJURP))
Alternative Name
Hjurp
Background
Holliday junction recognition protein is a protein in humans that is encoded by the HJURP gene. HJURP (holliday junction recognition protein) is a protein coding gene. Diseases associated with HJURP include fibrillary astrocytoma. Among its related pathways are DNA damage and chromosome maintenance. Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds holliday junctions.