FES antibody (AA 13-822)

Catalog No. ABIN7870485

The Rabbit Polyclonal anti-FES antibody is suitable to detect FES in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for FES antibody (AA 13-822) (ABIN7870485)

Target: FES (Feline Sarcoma Oncogene (FES))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FES antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FES Antibody

Binding Specificity: AA 13-822

Purpose: Fes/Fps Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H13-R822) was used as the immunogen for the Fes/Fps antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fes/Fps antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Fes/Fps antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FES

Target: FES (Feline Sarcoma Oncogene (FES))

Alternative Name: Fes/Fps

Background: FES (feline sarcoma oncogene) is an enzyme that in humans is encoded by the FES gene. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2