BIM antibody (AA 134-160)

Catalog No. ABIN7870529

This Rabbit Polyclonal antibody specifically detects BIM in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for BIM antibody (AA 134-160) (ABIN7870529)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BIM Antibody

Binding Specificity: AA 134-160

Purpose: Bcl-2-like protein 11 Antibody / BCL2L11 / Bim

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 134-160 from the human protein was used as the immunogen for the Bcl-2-like protein 11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Bcl-2-like protein 11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Bcl-2-like protein 11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: Bcl-2-like protein 11

Background: Bcl-2-like protein 11, also called BCL2L11 and Bim, belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator.

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity