Recombinant Topoisomerase II alpha antibody (AA 1352-1493)

Catalog No. ABIN7870549

The Mouse Monoclonal anti-Topoisomerase II alpha antibody (Clone rTOP2A-6629) (ABIN7870549) specifically detects Topoisomerase II alpha in IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant Topoisomerase II alpha antibody (AA 1352-1493) (ABIN7870549)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RTOP2A-6629

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: AA 1352-1493

Purpose: Recombinant Topoisomerase II alpha Antibody / TOP2A (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 1352-1493 was used as the immunogen for the recombinant Topoisomerase II alpha antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Topoisomerase II alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Topoisomerase II alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: Topoisomerase II alpha

Background: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and re-ligating the broken strand. [UniProt]

UniProt: P11388

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases