LONP1 antibody (AA 137-320)

Catalog No. ABIN7870574

This Rabbit Polyclonal antibody specifically detects LONP1 in WB, ELISA, IF, IHC (p), IP and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LONP1 antibody (AA 137-320) (ABIN7870574)

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LONP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-LONP1 Antibody

Binding Specificity: AA 137-320

Purpose: LONP1 Antibody

Purification: Affinity purified

Immunogen: Amino acids R137-A320 from the human protein were used as the immunogen for the LONP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LONP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LONP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Alternative Name: LONP1

Background: Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.

UniProt: P36776