The Rabbit Polyclonal anti-GALE antibody (ABIN7870681) specifically detects GALE in WB, IF, IHC (p) and FACS.
The antibody is reactive with Human samples.
GALE
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
The stated application concentrations are suggested starting points. Titration of the UDP-glucose 4-epimerase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Aliquot the UDP-glucose 4-epimerase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
GALE
(UDP-Galactose-4-Epimerase (GALE))
Alternative Name
UDP-glucose 4-epimerase
Background
UDP-galactose-4-epimerase catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids.