BMI1 antibody (AA 142-326)

Catalog No. ABIN7870689

The Mouse Monoclonal anti-BMI1 antibody is suitable to detect BMI1 in samples from Human and Mouse. It has been validated for WB, IF and IHC (p).

Quick Overview for BMI1 antibody (AA 142-326) (ABIN7870689)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BMI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: BMI1-2823

Product Details anti-BMI1 Antibody

Binding Specificity: AA 142-326

Purpose: BMI1 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 142-326) was used as the immunogen for this BMI1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the BMI1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the BMI1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Alternative Name: BMI1

Background: The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.

UniProt: P35226

Pathways: Cell Division Cycle, Autophagy