Recombinant Topoisomerase II alpha antibody (AA 1431-1531)

Catalog No. ABIN7870709

This Rabbit Monoclonal antibody specifically detects Topoisomerase II alpha in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Topoisomerase II alpha antibody (AA 1431-1531) (ABIN7870709)

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Topoisomerase II alpha antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TOP2A-4397R

Product Details anti-Topoisomerase II alpha Antibody

Binding Specificity: AA 1431-1531

Purpose: Recombinant TOP2A Antibody / Topoisomerase II alpha

Purification: Protein A affinity chromatography

Immunogen: A portion of amino acids 1431-1531 from the human protein was used as the immunogen for the recombinant TOP2A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant TOP2A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TOP2A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Topoisomerase II alpha

Target: Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

Alternative Name: TOP2A

Background: The topoisomerase II is the predominant mechanism of resistance to several chemotherapeutic agents.

UniProt: P11388

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases