Surfactant Protein C antibody (AA 144-173)

Catalog No. ABIN7870717

The Rabbit Polyclonal anti-Surfactant Protein C antibody (ABIN7870717) specifically detects Surfactant Protein C in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Surfactant Protein C antibody (AA 144-173) (ABIN7870717)

Target: Surfactant Protein C (SFTPC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Surfactant Protein C Antibody

Binding Specificity: AA 144-173

Purpose: Pulmonary surfactant-associated protein C Antibody / SFTPC

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 144-173 from the human protein was used as the immunogen for the Pulmonary surfactant-associated protein C antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Pulmonary surfactant-associated protein C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Pulmonary surfactant-associated protein C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Alternative Name: Pulmonary surfactant-associated protein C

Background: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

UniProt: P11686