CA9 antibody (AA 146-414)

Catalog No. ABIN7870733

This Rabbit Polyclonal antibody specifically detects CA9 in WB, ELISA, FACS and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for CA9 antibody (AA 146-414) (ABIN7870733)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CA9 Antibody

Binding Specificity: AA 146-414

Purpose: Carbonic Anhydrase IX Antibody / CA9

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D146-D414) was used as the immunogen for the Carbonic Anhydrase IX antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Carbonic Anhydrase IX antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Carbonic Anhydrase IX antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: Carbonic Anhydrase IX

Background: Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

UniProt: Q16790