SPDYA antibody (AA 147-175)
Quick Overview for SPDYA antibody (AA 147-175) (ABIN7870739)
Target
See all SPDYA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 147-175
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Purpose
- Speedy protein A Antibody / SPDYA / Spy1
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 147-175 from the human protein was used as the immunogen for the Speedy protein A antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the Speedy protein A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Speedy protein A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SPDYA (Speedy Homolog A (SPDYA))
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Alternative Name
- Speedy protein A
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Background
- SPDYA (speedy homolog A (Drosophila)) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
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UniProt
- Q5MJ70
Target
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