Cadherin 13 antibody (AA 149-692)

Catalog No. ABIN7870778

This Rabbit Polyclonal antibody specifically detects Cadherin 13 in WB, ELISA, FACS, IF and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for Cadherin 13 antibody (AA 149-692) (ABIN7870778)

Target: Cadherin 13 (CDH13)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cadherin 13 Antibody

Binding Specificity: AA 149-692

Purpose: Cadherin 13 Antibody / CDH13 / H Cadherin

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids E149-A692) was used as the immunogen for the Cadherin 13 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cadherin 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Cadherin 13 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: Cadherin 13

Background: H-cadherin (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization