T-Box 1 antibody (AA 15-43)

Catalog No. ABIN7870792

The Rabbit Polyclonal anti-T-Box 1 antibody (ABIN7870792) specifically detects T-Box 1 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for T-Box 1 antibody (AA 15-43) (ABIN7870792)

Target: T-Box 1 (TBX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-T-Box 1 Antibody

Binding Specificity: AA 15-43

Purpose: Brachyury Antibody / Protein T / TBXT

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 15-43 from the human protein was used as the immunogen for the Brachyury antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Brachyury antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Brachyury antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for T-Box 1

Target: T-Box 1 (TBX1)

Alternative Name: Brachyury

Background: The protein encoded by the TBXT gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

UniProt: O15178

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation