POT1 antibody (AA 15-638)

Catalog No. ABIN7870800

The Rabbit Polyclonal anti-POT1 antibody is suitable to detect POT1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for POT1 antibody (AA 15-638) (ABIN7870800)

Target: POT1 (Protection of Telomeres 1 (POT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-POT1 Antibody

Binding Specificity: AA 15-638

Purpose: POT1 Antibody

Purification: Affinity purified

Immunogen: Recombinant rat protein (amino acids N15-V638) was used as the immunogen for the POT1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the POT1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the POT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Alternative Name: POT1

Background: Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Pathways: Cell Division Cycle, Telomere Maintenance