DBN1 antibody (AA 150-281)

Catalog No. ABIN7870878

The Mouse Monoclonal anti-DBN1 antibody is suitable to detect DBN1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for DBN1 antibody (AA 150-281) (ABIN7870878)

Target: DBN1 (Drebrin 1 (DBN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DBN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: DBN1-2880

Product Details anti-DBN1 Antibody

Binding Specificity: AA 150-281

Purpose: Drebrin Antibody / Debrin 1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Drebrin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Alternative Name: Drebrin

Background: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

UniProt: Q16643

Pathways: Maintenance of Protein Location