DBN1 antibody (AA 150-281)

Catalog No. ABIN7870881

The Mouse Monoclonal anti-DBN1 antibody is suitable to detect DBN1 in samples from Human. It has been validated for IHC (p).

Quick Overview for DBN1 antibody (AA 150-281) (ABIN7870881)

Target: DBN1 (Drebrin 1 (DBN1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DBN1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DRBP1-1

Product Details anti-DBN1 Antibody

Binding Specificity: AA 150-281

Purpose: Drebrin 1 Antibody

Purification: Protein G affinity chromatography

Immunogen: Amino acids 150-281 were used as the immunogen for the Drebrin 1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Drebrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Alternative Name: Drebrin 1

Background: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity). [UniProt]

UniProt: Q16643

Pathways: Maintenance of Protein Location