The Mouse Monoclonal anti-BARX1 antibody (Clone BARX1-2759) (ABIN7871008) specifically detects BARX1 in IHC (p).
The antibody is reactive with Human samples.
Optimal dilution of the BARX1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the BARX1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
BARX1
(BARX Homeobox 1 (BARX1))
Alternative Name
BARX1
Background
BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.