RAB7A antibody (AA 156-197)

Catalog No. ABIN7871017

The Rabbit Polyclonal anti-RAB7A antibody (ABIN7871017) specifically detects RAB7A in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RAB7A antibody (AA 156-197) (ABIN7871017)

Target: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB7A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB7A Antibody

Binding Specificity: AA 156-197

Purpose: RAB7A Antibody

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (A156-R197) was used as the immunogen for the RAB7A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RAB7A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RAB7A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RAB7A

Target: RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))

Alternative Name: RAB7A

Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.

UniProt: P51149

Pathways: EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome