Cathepsin E antibody (AA 157-187)

Catalog No. ABIN7871019

The Rabbit Polyclonal anti-Cathepsin E antibody is suitable to detect Cathepsin E in samples from Human, Mouse and Rat. It has been validated for WB, FACS and IHC (p).

Quick Overview for Cathepsin E antibody (AA 157-187) (ABIN7871019)

Target: Cathepsin E (CTSE)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin E antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cathepsin E Antibody

Binding Specificity: AA 157-187

Purpose: CTSE Antibody / Cathepsin E

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 157-187 from the human protein was used as the immunogen for the CTSE antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the CTSE antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CTSE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cathepsin E

Target: Cathepsin E (CTSE)

Alternative Name: CTSE

Background: CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.

UniProt: P14091