CPN1 antibody (AA 158-208)

Catalog No. ABIN7871027

This Rabbit Polyclonal antibody specifically detects CPN1 in WB, ELISA, FACS and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CPN1 antibody (AA 158-208) (ABIN7871027)

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-CPN1 Antibody

Binding Specificity: AA 158-208

Purpose: CPN1 Antibody / Carboxypeptidase N catalytic chain

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D158-N208) was used as the immunogen for the CPN1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CPN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CPN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CPN1

Target: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Alternative Name: CPN1

Background: Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene. Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits, this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

UniProt: P15169

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process