Mu Opioid Receptor 1 antibody (AA 161-187)

Catalog No. ABIN7871106

The Rabbit Polyclonal anti-Mu Opioid Receptor 1 antibody is suitable to detect Mu Opioid Receptor 1 in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for Mu Opioid Receptor 1 antibody (AA 161-187) (ABIN7871106)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mu Opioid Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Mu Opioid Receptor 1 Antibody

Binding Specificity: AA 161-187

Purpose: Mu-type Opioid Receptor Antibody / OPRM1 / MOR-1

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 161-187 from the human protein was used as the immunogen for the Mu-type Opioid Receptor antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Mu-type Opioid Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Mu-type Opioid Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Alternative Name: Mu-type Opioid Receptor

Background: OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998). There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane