MOV10 antibody (AA 167-772)

Catalog No. ABIN7871196

The Rabbit Polyclonal anti-MOV10 antibody is suitable to detect MOV10 in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for MOV10 antibody (AA 167-772) (ABIN7871196)

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOV10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MOV10 Antibody

Binding Specificity: AA 167-772

Purpose: MOV10 Antibody

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids H167-Q772) was used as the immunogen for the MOV10 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MOV10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MOV10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MOV10

Target: MOV10 (Moloney Leukemia Virus 10 (MOV10))

Alternative Name: MOV10

Background: Putative helicase MOV-10 is an enzyme that in humans is encoded by the MOV10 gene. MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retro-transposition of endogenous retroelements in mammals. MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages. It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.

UniProt: Q9HCE1

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome