Villin 1 antibody (AA 179-311)
Quick Overview for Villin 1 antibody (AA 179-311) (ABIN7871351)
Target
See all Villin 1 (VIL1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Binding Specificity
- AA 179-311
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Purpose
- Villin Antibody (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogen
- A recombinant human partial protein (amino acids 179-311) was used as the immunogen for this Villin antibody.
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Isotype
- IgG1, kappa
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Application Notes
- Optimal dilution of the Villin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Villin 1 (VIL1)
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Alternative Name
- Villin
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Background
- Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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UniProt
- P09327
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Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
Target
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