Villin 1 antibody (AA 179-311)

Catalog No. ABIN7871353

The Mouse Monoclonal anti-Villin 1 antibody (Clone VIL1-1314-VIL1-2376) (ABIN7871353) specifically detects Villin 1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Villin 1 antibody (AA 179-311) (ABIN7871353)

Target: Villin 1 (VIL1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Villin 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: VIL1-1314-VIL1-2376

Product Details anti-Villin 1 Antibody

Binding Specificity: AA 179-311

Purpose: Villin Antibody Cocktail (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 179-311) was used as the immunogen for this Villin antibody cocktail.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Villin antibody cocktail should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Villin antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Villin 1

Target: Villin 1 (VIL1)

Alternative Name: Villin

Background: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization