FGF3 antibody (AA 18-239)

Catalog No. ABIN7871402

This Rabbit Polyclonal antibody specifically detects FGF3 in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FGF3 antibody (AA 18-239) (ABIN7871402)

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FGF3 Antibody

Binding Specificity: AA 18-239

Purpose: FGF3 Antibody / Fibroblast growth factor 3

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids A18-H239) was used as the immunogen for the FGF3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the FGF3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the FGF3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FGF3

Target: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Alternative Name: FGF3

Background: INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

UniProt: P11487

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway