FOLR2 antibody (AA 18-46)

Catalog No. ABIN7871424

The Rabbit Polyclonal anti-FOLR2 antibody is suitable to detect FOLR2 in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for FOLR2 antibody (AA 18-46) (ABIN7871424)

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FOLR2 Antibody

Binding Specificity: AA 18-46

Purpose: FOLR2 Antibody / Folate Receptor beta

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 18-46 from the human protein were used as the immunogen for the FOLR2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FOLR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FOLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FOLR2

Target: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Alternative Name: FOLR2

Background: FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

UniProt: P14207

Pathways: Dicarboxylic Acid Transport