Macro H2A.2 (AA 181-340) antibody
This Rabbit Polyclonal antibody specifically detects Macro H2A.2 in ELISA, WB, FACS, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7871456
$625.62
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 2 to 4 Business Days
Quick Overview for Macro H2A.2 (AA 181-340) antibody (ABIN7871456)
Target
Macro H2A.2
Reactivity
Human, Mouse, Rat
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Binding Specificity
- AA 181-340
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Purpose
- MACROH2A2 Antibody / H2AFY2
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Purification
- Antigen affinity chromatography
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Immunogen
- An E.coli-derived human recombinant protein (amino acids D181-D340) was used as the immunogen for the MACROH2A2 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the MACROH2A2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the MACROH2A2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Macro H2A.2
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Alternative Name
- MACROH2A2
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Background
- Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation.
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UniProt
- Q9P0M6
Target
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