Resistin antibody (AA 19-108)

Catalog No. ABIN7871549

This Mouse Monoclonal antibody specifically detects Resistin in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Resistin antibody (AA 19-108) (ABIN7871549)

Target: Resistin (RETN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Resistin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RETN-4325

Product Details anti-Resistin Antibody

Binding Specificity: AA 19-108

Purpose: Resistin Antibody / RETN

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human RETN protein (within amino acids 19-108) was used as the immunogen for the Resistin antibody.

Isotype: IgG2, lambda

Application Details

Application Notes: Optimal dilution of the Resistin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Resistin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: Resistin

Background: The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like alpha is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, resistin-like beta, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like beta expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

UniProt: Q9HD89

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration