TREM2 antibody (AA 19-131)

Catalog No. ABIN7871557

The Rabbit Polyclonal anti-TREM2 antibody (ABIN7871557) specifically detects TREM2 in WB, ELISA and FACS. The antibody is reactive with Rat samples.

Quick Overview for TREM2 antibody (AA 19-131) (ABIN7871557)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TREM2 Antibody

Binding Specificity: AA 19-131

Purpose: Trem2 Antibody

Purification: Affinity purified

Immunogen: A rat recombinant partial protein (amino acids L19-D131) was used as the immunogen for the Trem2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Trem2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Trem2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: Trem2

Background: Triggering receptor expressed on myeloid cells 2 also known as TREM-2 is a protein that in humans is encoded by the TREM2 gene. This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: D3ZZ89